Galileo ONE

A Sample-to-Result Integrated Workflow

Galileo ONE is a metagenomic NGS (mNGS) platform that takes the user from a primary sample to quantitative results for over 1300 microbes. This turnkey workflow combines the Galileo ONE Sample Preparation Kit with automated analysis and reporting using our cloud-based Galileo Analytics and assumes the user has access to an Illumina sequencer.

Cutting-Edge Technology in Your Own Lab

Galileo ONE empowers users to easily bring mNGS technology in-house, providing greater flexibility and control over assay parameters as well as shorter turnaround time. No more black box pipelines or waiting for samples to ship. And because Galileo ONE is a fully integrated workflow with full process controls included, it eliminates the need for bioinformatics expertise to get started.

Get the Most Insight Out of Every Sample

Unlike a targeted approach which provides limited insight, Galileo ONE is a truly unbiased approach to microbial detection. The platform can detect organisms that cannot be cultured, as well as those that require special conditions to grow. And with parallel DNA and RNA workflows, Galileo ONE enables detection and quantification of greater than 99% of known human pathogens* from a single sample using one test.
*Foresight. Infectious Diseases: Preparing for the Future. Office of Science and Innovation; London, UK : 2006.

Detect All in One Sample

  • Bacteria
  • Viruses
  • Fungi
  • Parasites

All Nucleic Acid Types

  • Double-stranded DNA
  • Single-stranded DNA
  • RNA

Integrated Controls

  • Background control
  • Internal control
  • External positive control

Get Started Today

Access to a sequencer is all that is required to begin using the Galileo ONE workflow for mNGS analysis.
Galileo ONE Features
Galileo ONE Benefits
Sample Type
Plasma, CSF, other liquid sample types
Minimal optimization to analyze multiple liquid
sample types.
Nucleic Acid Type
DNA (double- and single-stranded) and RNA
Detects all microbial types, including RNA viruses.
Minimum Input Volumes
1.2 mL (0.8 mL for DNA, 0.4 mL for RNA)
Maximizes analytical sensitivity while minimizing use of precious samples.
Compatible with all Illumina platforms
Utilizes sequencers found in most sequencing cores and labs.
Cloud-based automated informatics pipeline
Ensures that only reference genomes meeting quality control standards are included in analysis.
Proprietary and manually curated set of
reference genomes.
Integrated control scheme enables real-time quality control monitoring of sequencing runs
and libraries.
Control Scheme
Full-process internal and external run controls, plus quantification controls.
Full-process internal and external run controls, plus quantification controls.
Microbial identification and quality control reports generated for each library.
Microbial identification and quality control reports generated for each library.
The Galileo ONE Sample Preparation Kits are available in three configurations: DNA-only, RNA-only, or Combo DNA+RNA. Each kit includes reagents and consumables needed to generate sample libraries, plus external, internal, and background controls. The Training Kit supports live and web-based training by our in-house experts on the Galileo ONE workflow and enables seamless implementation and routine use in your facility. Access to Galileo ONE Analytics is included for each kit through our user-friendly web app and customizable APIs.

Contact Us

Talk with us to explore how we can work together. Just have a question? We would love to hear from you.
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