Dovetail® Hi-C Solutions

Dovetail Hi-C solutions all use sequence-independent nucleases to deliver high resolution and uniform base-coverage, and a novel dual cross-linking approach to enrich for long-range interactions. Our optimized, reproducible, off-the-shelf kits are validated across a wide range of samples and species and are ready to use so there’s no reagent qualification required. Choose the best kit for your research and take your discovery to the next dimension.

Dovetail® Micro-C Kit

Get ultra-high resolution or decrease sequencing costs – it’s up to you
For those looking for fine-scale topology mapping down to the mono-nucleosome level (150 – 200 bp conformation). Unlock your genome architecture one nucleosome at a time. For those looking to save on Hi-C experiment costs. Higher signal-to-noise ratios at 1 kbp conformation resolution translates to confident matrices building at just a fraction of the cost.
Ideal For:
Non-targeted Genome Topology
Hybrid Capture Compatible

Dovetail® TopoLink Kit

The easiest and fastest Hi-C Kit - Period
For those looking to add Hi-C to their toolbox or replace their current Hi-C with a significantly faster and cost effective alternative, Dovetail TopoLink is the kit for you. Generate superior data in less than half the time. The Dovetail TopoPrep uses Tn5 to simplify and streamline the workflow reducing overall time without compromising data.
Ideal For:
Non-Targeted Genome Topology

Dovetail® HiChIP MNase Kit

Get a 3D take on your ChIP-seq data
For those looking to add Hi-C to your ChIP-seq. Explore how primary protein binding and protein-mediated chromatin interactions influence gene expression – in a single library. It’s ChiP-Seq, just with 3D interaction information.
Ideal For:
Protein Directed Topology

Dovetail® Omni-C® Kit

Produce the highest quality genome assembly
For those looking for the ultimate scaffolding tool, Dovetail Omni-C data delivers uniform, shotgun-like sequence coverage enabling genotyping and haplotype phasing, alongside long-range information charateristic of Hi-C data. Take your assembly to the next level with a fully haplotype-resolved genome.
Ideal For:
Large Variant Detection


Haplotype Phasing
Hybrid Capture Compatible

Dovetail® Pan Promoter Kit

Focus on promoter-enhancer interactions
For those looking to facilitate Hi-C studies on large sample cohorts and save sequencing costs, specifically target gene promoter regions using hybrid capture technology and map the promoter/enhancer interaction landscape.
Ideal For:
Targeted Genome Topology
Chromatin Topology
Whole Genome Ultra
High-Resolution Topology
Whole Genome Rapid
High-Resolution Topology
Protein Anchored Topology
Enhancer Promoter Interactions
Genetic Variation
Large Structural
Variant Detection
Haplotype Phasing
Genetic Genome Assembly
Genome Scafolding
Hybrid Capture Compatible
Dovetail Assay
Pan Promoter
* Workflow also requires the Dovetail® Micro-C Kit
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