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Catalog #: 21010

Dovetail® TopoLink™ Kit

Accelerate Your Hi-C Studies

Ideal For:
Non-targeted Genome Topology
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TopoLink™ Kit Video Overview

Unlock the Future of Hi-C Data Generation with the Dovetail® TopoLink Assay

Are you a researcher delving into genome-wide chromatin conformation using traditional Hi-C methods? If so, you'll want to explore the groundbreaking Dovetail TopoLink™ Assay. This innovative solution not only simplifies the Hi-C workflow but also tackles high sequencing costs and uneven genomic coverage. And the best part? The entire process can be completed in just one day!
WATCH VIDEO

Sample to Sequencing Library – In Less than One Day

TopoLink Assays are the only complete solution that integrates proximity ligation with NGS library prep. Whether you are mapping A/B compartments, identifying TAD boundaries, or capturing chromatin loops, the TopoLink Assay offers the fastest end-to-end workflow.

  • Accelerated workflow – sample to library in less than a day.
  • Reduced cost per datapoint – up to 12-fold lower than traditional Hi-C.
  • Improved signal-to-noise – detect more topological features.
  • Uniform sequence coverage – higher feature call accuracy.

Increase the Discovery Rate of Genomic Interactions Features

Dovetail® TopoLink™ data delivers unbiased and uniform genomic coverage, resulting in richer contact matrices and increased chromatin loop detection compared to Hi-C data.

Unbiased Genome Coverage Equals Improved Accuracy

The uniform sequence coverage generated by Dovetail® TopoLink™ libraries produces the most accurate chromatin interaction map possible. Where the non-uniform restriction enzyme site distribution associated with traditional Hi-C methods often skews signals, you can be confident in the position of interactions detected by the Dovetail TopoLink Assay.

Customer Testimonials

“I have found the Dovetail® TopoLink™ Kit to be easy to use and not affected by tissue or cell morphology. It’s been very well suited to my study of looping interactions compared to the other kits I have used.”
Benjamin Lebeau, Research Assistant, Nanyang Technological University

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