Featured Dovetail® Webinars
Dovetail® Conferences & Tradeshows
Dovetail® Webinar Recordings
Steven Salzberg, Ph.D. Johns Hopkins University
Anthony Geneva, Ph.D. Drexel University
Susan Strickler, Ph.D. Boyce Thompson Institute
Vanessa L. González, Ph.D. Smithsonian Institution
We generated a reference-quality genome Solemya velum (Bivalvia: Protobranchia) to allow us to test hypotheses about mollusc genome evolution and the symbiotic interactions in marine molluscs. 10X Genomics, PacBio Long-reads and Hi-C data was leveraged for molluscan genome assembly. Iterations and combinations of each data type have resulted in a 2.4 GB reference genome with a scaffold N50 of 200 MB and a BUSCO completeness score of 93.7%.
Harris Lewin, Ph.D.UC Davis
Trace the directed evolution of 28 genome assemblies of the Narwhal, an iconic cetacean known at the “unicorn of the sea”. While understanding the evolution and amazing phenotypes of the Narwhal is the ultimate goal, the evolution of genome assemblies from short-read to long read-based assemblies with Dovetail scaffolding has been an interesting scientific journey in itself. Different sequencing approaches will be discussed in the light of genome assembly evolution, and their importance for understanding genome biology.
Cory Padilla, Ph.D. Dovetail Genomics
Key discussion points:
– The role of genome conformation in gene regulation
– Why integrating conformation data with genotyping data can provide a more complete view of variants
– How to capture variants (SNVs and structural variants) with conformation in a single sequencing library
Cory Padilla, Ph.D. Dovetail Genomics
Dirk Hockemeyer, Ph.D.
In this talk, Dr. Hockemeyer will discuss the use of Dovetail® Hi-C technology to assemble Indian and Chinese muntjac genomes to investigate telomere biology and chromosome fusion events in human cancer.
Presented live on December 10th, 2020
David Sinclar, Ph.D.Harvard Medical School
You’ll learn:
– What makes Micro-C different from Hi-C
– Wet lab process (method overview, QC metrics)
– Data processing Micro-C