The LinkPrep^™ Assay is the only complete solution that integrates proximity ligation with NGS library prep. Whether you are mapping A/B compartments, identifying TAD boundaries, or capturing chromatin loops, this Hi-C assay offers the fastest end-to-end workflow.

• Accelerated workflow – sample to library in a single day.
• Reduced cost per datapoint – up to 12-fold lower than traditional Hi-C.
• Improved signal-to-noise – detect more topological features.
• Uniform sequence coverage – higher feature call accuracy.

Dovetail^® LinkPrep™ data delivers unbiased and uniform genomic coverage, resulting in richer contact matrices and increased chromatin loop detection compared to Hi-C data.

The uniform sequence coverage generated by Dovetail^® LinkPrep™ libraries produces the most accurate chromatin interaction map possible. Where the non-uniform restriction enzyme site distribution associated with traditional Hi-C methods often skews signals, you can be confident in the position of interactions detected by the Dovetail LinkPrep Assay.